Biotin and derivatives
Medchemexpress LLC Mal-PEG3-C1-NHS ester | 2230016-26-7 | 95.0% | 384.34 g/mol | C16H20N2O9 | 50 MG
Mal-PEG3-C1-NHS ester is a non-cleavable 3-unit polyethylene glycol (PEG) linker bearing a maleimide and an N-hydroxysuccinimide (NHS) ester. It is supplied for research use to facilitate conjugation between amine and thiol groups during antibody-drug conjugate (ADC) synthesis, and is provided as a solution for low-temperature storage.
- Non-cleavable 3-unit polyethylene glycol linker.
- Terminal maleimide and NHS ester functional groups for thiol and amine coupling.
- Suitable for antibody-drug conjugate (ADC) synthesis.
- Purity approximately 95.0%.
- Supplied as a solution; store at -20°C for up to 2 years.
Medchemexpress LLC NOTA-NHS ester | 1338231-09-6 | MFCD30747764 | 90.0% | 400.38 | C16H24N4O8 | 10 MG
NOTA-NHS ester is an N-hydroxysuccinimide (NHS) ester used to conjugate a NOTA chelator to biomolecules for subsequent fluorescent or radioactive nuclide labeling in research applications. It is supplied as a solid reagent with defined molecular characteristics for use in radiopharmaceutical and probe development.
- Provides an NHS-ester functional group for amine conjugation.
- Suitable for fluorescent labeling and radioactive nuclide labeling applications.
- Documented molecular formula C16H24N4O8 and molecular weight 400.38.
- Available in small research pack sizes for synthesis and probe preparation.
- Typically soluble in DMSO for conjugation reactions.
Medchemexpress LLC 4,7,12-Trioxa-10-azatetradecanoic acid, 13,13-dimethyl-11-oxo-, 2,5-dioxo-1-pyrrolidinyl ester | 2183440-73-3 | ≥98.0% | C16H26N2O8 | 1 G
Boc-NH-PEG2-C2-NHS ester is an alkyl/ether-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs leverage the intracellular ubiquitin-proteasome system for selective degradation of target proteins. This product is a white to off-white solid and is intended for research use only.
- Alkyl/ether-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- White to off-white solid appearance
- For research use only
Medchemexpress LLC Mal-C2-NHS ester | 103750-03-4 | 99.3% | 294.26 g/mol | C13H14N2O6 | 100 MG
Mal-C2-NHS ester is a noncleavable antibody-drug conjugate (ADC) linker that contains a maleimide group and an N-hydroxysuccinimide (NHS) ester; it is used to conjugate payloads to antibodies via thiol and amine chemistry during ADC synthesis.
- Noncleavable ADC linker suitable for antibody conjugation.
- Contains maleimide and NHS ester reactive groups for thiol and amine coupling.
- High purity, suitable for research applications.
- Molecular weight 294.26 g/mol and formula C13H14N2O6.
- Available in small-scale packages for synthesis and optimization studies.
Medchemexpress LLC Biotin methyl ester 500mg
Biotin methyl ester is a biochemical reagent that can be used as a biological material or organic compound for life science related research
![Medchemexpress LLC 2,5-pyrrolidinedione, 1,1'-[oxybis[(1-oxo-3,1-propanediyl)oxy]]bis- (9CI) | 65869-64-9 | MFCD20226397 | 97.0% | 356.28 | C14H16N2O9 | 500 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000203008.png-250.jpg)
Medchemexpress LLC 2,5-pyrrolidinedione, 1,1'-[oxybis[(1-oxo-3,1-propanediyl)oxy]]bis- (9CI) | 65869-64-9 | MFCD20226397 | 97.0% | 356.28 | C14H16N2O9 | 500 MG
Bis-PEG1-NHS ester is a non-cleavable 1-unit polyethylene glycol (PEG) linker designed for antibody-agent conjugation (ADC) research applications. It contains two N-hydroxysuccinimide (NHS) ester reactive groups that enable conjugation to primary amines on proteins or payload molecules, and is supplied with high purity for analytical and synthetic workflows.
- Non-cleavable 1-unit PEG linker for antibody-agent conjugation.
- Contains two NHS ester reactive groups for conjugation to primary amines.
- Intended for research use in ADC linker synthesis and bioconjugation workflows.
- Purity 97.0% by HPLC.
- Available in a 500 MG pack size suitable for preparative work.
Medchemexpress LLC 5-maleimido-pentanoic N-hydroxysuccinimide ester | 103750-03-4 | MFCD01318603 | 99.3% | 294.26 g/mol | C13H14N2O6 | 50 MG
Mal-C2-NHS ester (5-maleimido-pentanoic N-hydroxysuccinimide ester) is a noncleavable antibody-drug conjugate (ADC) linker that features a maleimide and an N-hydroxysuccinimide (NHS) ester for bioconjugation to thiol and amine groups during ADC synthesis.
- Noncleavable ADC linker suitable for antibody-drug conjugation.
- Maleimide group enables selective thiol coupling.
- N-hydroxysuccinimide (NHS) ester enables amine coupling.
- High purity and defined molecular weight for reproducible conjugation.
Medchemexpress LLC Mal-PEG1-NHS ester | 1807518-72-4 | 310.26 g/mol | C13H14N2O7 | 1 G
Mal-PEG1-NHS ester is a PEG-based bifunctional linker containing a maleimide group and an N-hydroxysuccinimide (NHS) ester. It is used for bioconjugation in the synthesis of antibody-drug conjugates (ADCs) and proteolysis-targeting chimeras (PROTACs), enabling selective thiol-to-amine coupling via maleimide and NHS chemistries.
- Bifunctional maleimide and NHS ester chemistry for thiol and amine coupling.
- PEG spacer increases solubility and reduces steric hindrance.
- Non-cleavable linker suitable for ADC and PROTAC synthesis.
- Available in multiple pack sizes, including 1 g for preparative use.
- Molecular weight 310.26 g/mol and formula C13H14N2O7.
Medchemexpress LLC FP-Biotin | 259270-28-5 | 99.1% | 592.75 | 10 MM * 1 ML
FP-Biotin is a potent organophosphorus toxicant suitable for identifying new biomarkers of organophosphorus toxicant exposure. It quantifies the activity of FAAH, ABHD6, and MAG-lipase. It is used in plasma studies where biotinylated peptides can be easily purified by binding to immobilized avidin beads. FP-Biotin demonstrates good reactivity with human AChE and BChE and is suitable for identifying organophosphorus toxicants reactive proteins.
- Potent organophosphorus toxicant
- Suitable for identifying new biomarkers of organophosphorus toxicant exposure
- Quantifies FAAH, ABHD6, and MAG-lipase activity
- Useful in plasma studies for easy purification of biotinylated peptides
- Reacts well with human AChE and BChE
- Identifies organophosphorus toxicants reactive proteins
Medchemexpress LLC Bis-PEG2-NHS ester | 65869-63-8 | 99.2% | 400.34 | C16H20N2O10 | 100 MG
Bis-PEG2-NHS ester is a non-cleavable two-unit polyethylene glycol (PEG) linker intended for antibody-agent conjugation (ADC) research applications. It provides NHS ester reactive groups for coupling to amines and is used in bioconjugation workflows to construct antibody-drug conjugates.
- Non-cleavable 2-unit PEG linker for antibody-agent conjugation.
- Purity 99.24% as reported by the manufacturer.
- Molecular weight 400.34 g/mol.
- Chemical formula C16H20N2O10.
- CAS number 65869-63-8.
- Appearance solid, white to off-white.
- Storage: powder -20°C (stable for 3 years); in solvent -80°C (6 months) or -20°C (1 month).
- Package size options include 100 mg, 250 mg, 1 g, 5 g, 10 g, and 50 g.
- Manufacturer documents available: data sheet, safety data sheet, certificate of analysis, handling instructions, H NMR, RP-HPLC, and mass spectrometry data.
Medchemexpress LLC Azido-PEG5-NHS ester | 1433996-86-1 | ≥98.0% | C17H28N4O9 | 100 MG
Azido-PEG5-NHS ester is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. It acts as a versatile click chemistry reagent, incorporating an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. This compound also supports strain-promoted alkyne-azide cycloaddition (SPAAC) reactions when used with molecules containing DBCO or BCN groups. It is intended for research use only.
- PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains an azide group
- Participates in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc)
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
Medchemexpress LLC Biotin-PEG7-amine | 1334172-76-7 | 98.0% | C26H50N4O9S | 50 MG
Biotin-PEG7-amine is a PEG-based PROTAC linker. It is utilized in the synthesis of PROTACs, which are molecules designed to exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. PROTACs achieve this by connecting two different ligands via a linker, one binding to an E3 ubiquitin ligase and the other to a target protein.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC N-Mal-N-bis(PEG2-NHS ester) | 2182601-73-4 | 98.9% | C29H38N4O15 | 100 MG
N-Mal-N-bis(PEG2-NHS ester) is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs are compounds containing two different ligands connected by a linker: one for an E3 ubiquitin ligase and the other for a target protein. They function by exploiting the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
Medchemexpress LLC Bis-PEG10 N-hydroxysuccinimide ester | 2221949-02-4 | 95.0% | 752.76 g/mol | C32H52N2O18 | 50 MG
Bis-PEG10 N-hydroxysuccinimide ester is a bifunctional PEG10-based NHS ester linker used for conjugation chemistry. It features two NHS-reactive termini separated by a ten-unit polyethylene glycol spacer, enabling efficient amine coupling, increased aqueous solubility, and flexible linker geometry for targeted conjugate assembly.
- Two NHS ester reactive groups for amine coupling.
- Ten-unit PEG spacer for improved solubility and flexibility.
- Suitable for linker assembly in PROTAC and ADC synthesis.
- Typical purity 95.0%.
- Appearance: colorless to off-white oil.
- Storage: pure form, -20°C; in solvent, -80°C for long-term storage.